Rolf Hoffmeyer Ringborg

Rolf Hoffmeyer Ringborg

Postdoc

DTU KEMITEKNIK
Institut for Kemiteknik

Danmarks Tekniske Universitet

Bygning 227, rum 254

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Nøgleord Process integration | Chemical Engineering | Biocatalysis | Microtechnology

Topic of thesis:  µ-Tools for Development of ω-Transaminase Processes

Starting date: October 2012

Background: M.Sc. in Chemical Engineering from Technical University of Denmark

Supervisors: John Woodley, Krist Gernaey and Ulrik Khrüne 

The focus of this project is to develop µ-technology and toolboxes that can be used for feasibility screening of new processes. The development will focus on the enzyme ω-transaminase, this catalyst has shown challenging difficulties in relation to thermodynamics and economic feasibility. It is believed that the use of microtechnological methods will contribute to the exploitation of ω-transaminase based technology significantly. Microtechnology will reduce the quantity of expensive and/or scarce resources needed for evaluation of potential process candidates. The technology should also potentially help to reduce the development time of biocatalysis based processes. The project is part of a European collaboration called BIOINTENSE and also features a consortium of 14 partners