Enzyme engineering. Enzyme activity and stability are improved through careful protein engineering in the BioProcess Engineering research centre. Photo: Thorkild Christiensen

Enzyme Engineering

The purpose of the Enzyme Engineering research in Bioeng is to discover and develop new enzymes for novel innovative reactions and products. The research is based on both advanced database mining, explorative enzyme discovery (biodiversity screening), and ingenious bioresource utilization, and employs state-of-the-art techniques and tools for cloning, evolution, microbial expression, purification, and characterization of enzymes.

Key research objectives include:
  • Development of new enzymes for extraction and modification of food ingredients

  • Design of innovative biocatalyzed reactions, including selective transglycosylation reactions

  • Enzymatic development of carbohydrate-based functional food ingredients

  • Provision of new understanding of enzyme structure-function relationships


Jørn Dalgaard Mikkelsen
DTU Kemiteknik